Gut-Brain Axis: Microbiome, Serotonin, and Mental Health Connection
Evidence analysis of the gut-brain axis: 90% of serotonin produced in gut, 70% of immune system in gastrointestinal tract. Microbiome influences mental health, immune function, and inflammation through vagus nerve signaling, microbial metabolites (SCFAs, tryptophan metabolites), and gut barrier integrity.