Chelation Therapy: Evidence, Indications, and Caveats
Explains when clinically supervised chelation is warranted, which agents are approved, the risks involved, and what the evidence says about “natural chelators.”
Cellular Health
Fasting, Autophagy, and Cellular Repair: Evidence Analysis
Fasting activates autophagy. That's the body's cellular recycling system, and it has implications for metabolic health, inflammation reduction, and disease prevention. This analysis examines the evidence, timing requirements, and clinical applications.
Turmeric: Maximizing Curcumin Absorption and Benefits
Explore how to maximize the health benefits of turmeric by understanding curcumin absorption, gut health, and cellular pathways.
Berberine: Supporting Diabetes, Cancer, and Cardiovascular Health
Exploring how berberine influences key cellular pathways to aid in diabetes management, cancer treatment, and cardiovascular protection through AMPK activation and metabolic regulation.
Gut-Brain Axis: Microbiome, Serotonin, and Mental Health Connection
Evidence analysis of the gut-brain axis: 90% of serotonin produced in gut, 70% of immune system in gastrointestinal tract. Microbiome influences mental health, immune function, and inflammation through vagus nerve signaling, microbial metabolites (SCFAs, tryptophan metabolites), and gut barrier integrity.
Centella Asiatica: Neuroprotection and Cognitive Enhancement
Evidence analysis of Centella asiatica (Gotu Kola): triterpenoids (asiatic acid, asiaticoside) for neuroprotection, wound healing, anxiety. In vitro/animal data strong; human cognitive evidence weak/inconsistent. Topical wound healing has moderate evidence.
Taurine: Potential Roles in Nerve Health and Remyelination
Explore the emerging research on taurine, an amino acid studied for its potential roles in supporting nerve health, oligodendrocyte function, and remyelination in preclinical models.
Lion's Mane Mushroom: NGF/BDNF Support and Cognitive Evidence
Evidence analysis of Lion's Mane (Hericium erinaceus): erinacines and hericenones stimulate NGF/BDNF production. Modest cognitive benefits in older adults with MCI (MMSE +0.8-1.5 points); inconsistent results in healthy young adults. NGF/BDNF support for spike-induced neurodegeneration, basal ganglia recovery, and hippocampal neuroprotection relevant to HAND criteria and Long COVID cognitive impairment.